Saturday, September 5, 2009

How Bo Obama Got His Curls

I have written about this before: the link between human genes and canine ones, especially when it comes to unlocking those that may carry the genetic causes of cancer and heart disease. Well, it turns out that Bo, the presidential pooch is quite a genetically diverse dog....

According to research done by Gordon Lark, an emeritus biology professor at the University of Utah, variations in just three genes are responsible for seven types of canine coats, including the curly (reputably hypo-allergenic) one that Bo sports. An article in the Philadelphia Inquirer highlighting Lark's research, notes that complex traits can arise from just a small number of canine genes, perhaps providing a clue into how similar ones work in humans.

The three genes investigated are RSP02, which is associated with mustaches and bushy eyebrows; FGF5, which determines the length of a dog's coat and KRT71 in which variations create curls. Short hair is the inherited form of all the genes, derived from wolf ancestors.

Dogs such as the bearded collie have variations on the FGF5 and RSP02 gene while curly haired dogs have variations on the FGF5 and KRT71 genes.

And some Portugese water dogs, including Bo Obama, have variations on all three genes, which makes him quite a genetic melting pot. Fitting don't you think?

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